11^th International Conference and Expo on Nanoscience and Molecular Nanotechnology October 20-22, 2016 ROME, ITALY

Mr. Parth Malik is presently working for his Ph.D. in the domain of biocompatible nanoemulsions for improving the structural efficacy of bioactive compound curcumin. He is a specialist in Nanobiotechnology and has papers is reputed Elsevier, Wiley Science and Hindawi Journals. He has also actively taught the subjects of Nanobiotechnology, Bioprocess Engineering and Genetic Engineering to graduate and post-graduate students

Curcumin is a very well-known natural polyphenolic compound, prevalent as the major ingredient of the familiar spice turmeric. Numerous studies have established its interesting immunomodulatory attributes, ranging from those of anticancer, antioxidant, antidiabetic, anti-inflammatory and several others. However, the most crucial hurdle has been the poor bioavailability of this bioactive compound, which is because of its poor aqueous solubility. Realizing this, we prepared the nanoemulsions of cottonseed oil with cationic, anionic and nonionic surfactants as potential carriers of curcumin with an aim to augment its antioxidant ability. The prepared nanoemulsions were characterized via density, surface tension and viscosity measurement at 298.15, 303.15 and 308.15 K. The antioxidant efficacy of curcumin loaded nanoemulsions was screened via DPPH free radical scavenging assay, wherein an RSA of more than 90% was observed. The reduced surface tension and increased viscosities signified efficient curcumin dispersion, enabled via characteristic thermodynamic shift

Shima Vaezi has fulfilled her Bachelor’s degree in Chemical Engineering from Azad University, Tehran in 2013. After that, she studied Master of Chemical Textile Engineering at Azad University, Tehran. She is researching on nanocapsules for drug delivery

The “Nanocapsules” are called to those structures which have been formed from an external thin layer and an internal great space. This is known as core/shell structure. In present experimental test, the O/W nanoemulsion/solvent evaporation method has been used for production of nano­medicine containing the turmeric oil. The main purpose of this research is to apply polymer alloy of alginat/poly (vinyl alcohol) as wall material in capsulation process of natural plant essential. In first step, blend of polymers were used in wall and it was formed by dissolving a certain amount of polymer of alginate and poly (vinyl alcohol) within water (concentration of 0:1, 0.25:0.75, 0.5:0.5, 0.75:0.25, 1:0 w/v). Later on, a certain amount of turmeric oil (concentration of 0.75%, 05%, 0.25% w/v) was dissolved within ethanol and then was added to the primary solution drop by drop. After that, a certain amount of Tween 80 as surfactant and also calcium chloride as crosslinking agent were added to final solvent. In next step, obtained solvent was subjected to sonication and after that it was evaporated by vacuum device. In this research, we investigated effect of various factors such as layer of polymer concentration changes, variant concentration of turmeric oil and variant time of sonication on the size of nanocapsules. Scanning electron microscope (SEM), Zetasizer device with dynamic light scattering (DLS) technique were used to investigate of morphology and size of nanocapsules. The results of (DLS) analyses have proven that the best combination percentage for structure of the polymer layer is alginate with concentration of 0.25% and Poly (vinyl alcohol) with concentration of 0.75%. Therefore, the optimum amount of used polymer in the wall and different concentration of turmeric oil as the core have been investigated. The results of DLS test have demonstrated that the optimum concentration of turmeric oil is 0.25% (w/v) within ethanol. Furthermore, the optimum duration of sonication just took around 45 minutes. As results, the size of nanocapsules has been obtained up to 50 nm, with the optimum amount of used polymer in the wall. Also, the size of produced nanocapsule has been obtained up to 91 nm in the optimum concentration of turmeric oil. Finally, 45 minutes sonication leads to production of 50 nm nanocapsules.

Nazanin Ghafari has completed her B.S. in Textile Engineering/ Textile Chemistry major on 2013 and her M.Sc in Nanofibrous Structure on 2015 from Islamic Azad University, Yadegar Imam, Shar-e-rey Branch and has been educating for Phd degree in Science and Research University. She has submitted papers in conferences below

Nanotechology is the study and application of extremely small things(a bout 1to100 nanometers)rnAnd can be used across all the other science fields, such as chemistry,biology,physics,materials sciences and engineering.rnPolymeric Nanofibers as one of the most known NanoTechnology products in which have huge potential applications in many fields due their high aspect ratio and porosity.The three dimensional feature of the product, results in having high capability in mechanical and biological properties.rnElectrospinning is a simple and inexpensive method of producing Nanofibers in which for their unique structure can be used in tissue engineering.rnPolyvynil Alcohal(PVA) is a biocompatible and water soluble synthetic polymer, that is easily electrospinning.Typically PVA is a soluble in water but in fact the water can decrease the solubility of some polymers, hence blending these polymers with PVA can solve this problem. In this work, PVA prepared by acetic acid which has less affection on degradation and it is of low toxicity. rnThe main objective of this work is focuses on effect of distance and voltage paramerts on morphology and diameter of nanofibers.The morphology of electrospun PVA nanofibers were characterized by using scanning electron microscope(SEM) and Fourier transform infrared spectrometer(FTIR).rn