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Kooshina Koosha

Kooshina Koosha

Islamic Azad University, Tehran, Iran

Title: Study of some effective parameters on characterization of gelatin nanofiber prepared from gelatin-acetic acid solution

Biography

Biography: Kooshina Koosha

Abstract

Electrospinnig is a simple, versatile and widely accepted technique to produce ultra-fine fibers ranging from nanometer to micron. Recently there has been great interest in developing this technique to produce nanofibers with novel properties and functionalities. Most of the works reported on electrospinning evolve on the synthetic biodegradable polymer for dozens of applications in medicine, energy, transportation and electronic devices. In biomedical applications, synthetic biodegradable polymers such as polyester regularly associated with poor biocompatibility and systemic or local reaction resulted from the acidic degradation products. Therefore, naturally occurring polymers such gelatin has been widely explored due to its biocompatibility , biodegradability, hydrophilic in nature and commercial availability at low cost. Gelatin is a natural biopolymer derived from collagens and has almost identical compositions and biological properties as those of collagens. Accordingly, this natural biopolymer could be useful for dozens of biomedical applications. In order to expand the range of applications and to produce uniform and very fine nanofibers, choosing a non-toxic solvent, which will not degrade the gelatin structure and investigation of electrospinning parameters, play an important role. In the present work, gelatin was prepared by acetic acid which has a less affection to degradation and is of low toxicity. The morphology of electrospun gelatin nanofibers was characterized using scanning electron microscope (SEM). FTIR measurements were performed in FTIR spectrometer to verify the composition of fibers for functional groups and determining whether acid has affected the gelatin structure or not